The comic book convention in my town has videogame, anime, etc stuff, but ultimately a lot of floorspace is taken up by cape comics, because it's a comic book convention, and I just don't... care about that?
Anime offerings tend to be largely the same limited stuff every year. Sailor Moon is the one thing that isn't shounen that you can count on finding - otherwise it's Naruto, One Piece, Dragon Ball, Demon Slayer, YGO, etc. FMA, but I haven't found anything 03 specific when that's the version I care about. And anime girl figurines from popular gatchas and isekais. I've never seen any vocaloid merch that isn't Miku at this con, outside of a single "official art on a solid background" button pin of Teto.
The best bet for diversity is Artist Alley in the back, because the front is all cape comics, mass-popularity shounen, sailor moon as the one shoujo or mahou shoujo offering, and pokemon - but it felt even less diverse this year than previous years. A bunch of stuff that's currently popular with Millenials, Zoomers, etc was barely present. No Umamusume at the whole con! Like one table with Deltarune stickers or prints. There was a decent bit of KPop Demon Hunters at multiple tables, but still less than I expected? NO Amazing Digital Circus or Murder Drones. (Though i did see a kid cosplaying one of the Murder Drones characters, that was cute - they had the syringe tail and everything!)
For what it's worth, out of the things I've listed - I don't personally care about Umamusume, or KPop Demon Hunters, or ADC or MD. But I do notice that both "new things" I'm personally invested in (such as Deltarune) and new things I'm not personally invested in are lacking.
(Also I do kind of wish that I could attend a con that had a nice array of actual panels, and not just merch...)
One nice thing is that there's a table just outside artist alley selling some 70's shoujo paraphernalia. They said they get the laminated magazine covers from a Japanese store that does the cover-lamination process to old magazines that are too damaged to sell wholesale. Looking at the inside side of the covers, you see all these vintage advertisements aimed at the target audience of the magazine - honestly just as neat as the gorgeous sparkle-eyed illustrations on the fronts, albiet in a different sort of way. A slice of pop culture history...
But yea, I wish my area had dedicated anime and videogame conventions.